Sara Hinds
Engineered muscle
cell networks with user defined, reproducible architecture can be
used to study the structural factors that contribute to tissue function
and potentially offer a therapeutic replacement therapy for diseased
tissue. As a graduate student I will focus on developing an electrical
pulse stimulator system to improve the properties of muscle bundle
constructs. An in-vitro bio-mimetic environment, including 3D tissue
architecture and electrical stimulation, may harmonize the integrated
cellular response of engineered muscle tissue thereby optimizing
functionality. In particular, the aim of my electrical stimulation
project is to improve bio-artificial muscle contractility.